Cryptococcus Tube Agglutination Systems
Tube Agglutination System for Antibody Detection
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In most cases of cryptococcosis, antigen concentration will exceed antibody and be detected in latex agglutination tests. However, in some cases and in some stages of the disease, antigen may not be present in excess and tests to detect antibody may be necessary to make a serological diagnosis. In Central Nervous System (CNS) cryptococcosis, antigen excess is present and detectable by latex agglutination in spinal fluid in the vast majority of cases. During successful antifungal therapy, it is not uncommon for antigen tests to become negative and antibody tests to become positive with rising titers. In non-CNS disease (e.g., pulmonary, osteolytic, etc.), antibody tests may be the only means for making a serological diagnosis, since tests for antigen may or may not be positive.
The YA-Crypto Tube Agglutination System is based upon the principle that yeast cells of weakly encapsulated Cryptococcus neoformans strains will agglutinate with specimens containing antibodies against C. neoformans. The system detects these antibodies when present and is both qualitative and semi-quantitative. It is most effective for detecting the antibodies of C. neoformans in the serum of patients with pulmonary and extra-pulmonary cryptococcus (non-meningeal); however, the spinal fluid of cryptococcal meningitis patients may also contain detectable levels of antibody, especially during and following successful therapy.
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Cryptococcus Tube Agglutination System
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CATALOG #
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DESCRIPTION
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UNIT
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YA1001
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YA-CRYPTO ANTIBODY TUBE AGGLUTINATION SYSTEM
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60 Tests
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Cryptococcus Tube Agglutination Reagents
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CATALOG #
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DESCRIPTION
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UNIT
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AC0000
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Anti-Cryptococcus Positive
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2 ml
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CW0000
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Cryptococcus Yeast Antigen (10X concentrate)
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10 ml
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GB0020
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Glycine Buffered Diluent with Albumin (GBDA, 10X concentrate)
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10 ml
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N80110
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Negative Control
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1 ml
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Immuno Mycologics, Inc. 2003
Telephone:405-360-4669 Toll
Free: 800-654-3639 Fax:405-364-1058
2700 Technology Pl
Norman, OK 73071 U.S.A.
info@immy.com
Immy provides the most comprehensive line of diagnostic products available in the study of Mycology.
We offer a variety of fungal test products for the following organisms: Cryptococcus neoformans, Coccidiodes immitis, Histoplasma capsulatum, Candida albicans, Sporothrix schenckii,
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