Cryptococcus Latex Agglutination Systems
Latex Agglutination Systems for Antigen Detection
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The Latex Antigen Detection System is a simple and rapid latex agglutination test for the qualitative and semi-quantitative detection of the capsular polysaccharide antigens of Cryptococcus neoformans in serum and cerebrospinal fluid (CSF). Cryptococcal antigen is frequently present in the serum of patients with pulmonary cryptococcosis and in the CSF and serum of patients with central nervous system involvement.
Currently, almost 50% of all cryptococcosis cases occur in HIV positive individuals. Other than in AIDS patients, cryptocooccosis occurs in normal individuals(rarely) and in subjects with impaired immune systems due to: 1) underlying diseases such as lupus erythematosis, sarcoidosis, leukemia, lymphoma and Cushing's disease; 2) immuno suppressive therapies such as corticosteroids, cytotoxic drugs and transplantation therapeutics.
Since its introduction by IMMY in 1982, Detacher Enzyme (DE), Pronase®, has proven to be a vital component. DE digests antibodies in immune complexes (the antigen is not affected), which can mask the detection of antigens. DE also eliminates rheumatoid factor, which can cause false positives.
"Pronase is a registered trademark of CALBIOCHEM Corporation.
You may wish to visit the
"Frequently Asked Questions" section about Latex-Crypto antigen tests.
Online Documents:
If you would like to read the product insert or download the NCCLS Format laboratory procedure.
Click here.
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Cryptococcus Latex Agglutination Systems
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CATALOG #
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DESCRIPTION
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UNIT
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CR1003
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LATEX-CRYPTO ANTIGEN SYSTEM
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Up to 50 Screening Tests
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CR1004
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LATEX-CRYPTO ANTIGEN SYSTEM
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Up to 120 Screening Tests
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CR1005
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LATEX-CRYPTO ANTIGEN SYSTEM
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Up to 240 Screening Tests
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Cryptococcus Latex Agglutination Reagents
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CATALOG #
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DESCRIPTION
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UNIT
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CB0010
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Low-Crypto-Cryptococcal Antigen Control
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1 ml
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CG0010
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Anti-Cryptococcal Latex Reagent
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3.5 ml
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CG0020
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Anti-Cryptococcal Latex Reagent
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1.5 ml
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DE0010
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Detacher Enzyme
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1.75 ml
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EI0010
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Enzyme Inhibitor (for DE)
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6 ml
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GB0020
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Glycine Buffered Diluent with Albumin (GBDA, 10X Concentrate)
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10 ml
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N80110
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Negative Control
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1 ml
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R20000
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Anti-Globulin Control
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2 ml
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Immuno Mycologics, Inc. 2003
Telephone:405-360-4669 Toll
Free: 800-654-3639 Fax:405-364-1058
2700 Technology Pl
Norman, OK 73071 U.S.A.
info@immy.com
Immy provides the most comprehensive line of diagnostic products available in the study of Mycology.
We offer a variety of fungal test products for the following organisms: Cryptococcus neoformans, Coccidiodes immitis, Histoplasma capsulatum, Candida albicans, Sporothrix schenckii,
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