Latex Agglutination (LA) Tests

Sporotichosis is an endemic fungal infection caused by S. schenckii with most case reports coming from the tropical and subtropical regions of the Americas. The LA-SPOROTHRIX test is a sensitive, rapid test that is useful for the presumptive diagnosis of sporotrichosis from patients with localized cutaneous, subcutaneous, disseminated subcutaneous or systemic forms of the disease.

Sera from patients with localized cutaneous lymphocutaneous or extracutaneous sporotrichosis may show titers that range from 1:8 to 1:512. An increasing titer or a sustained high titer is helpful in the diagnosis of pulmonary sporotrichosis. The LA test has limited prognostic value. The LA test has a sensitivity of 100%, 86%, 73%, and 56% for disseminated, articular, pulmonary, and cutaneous disease, respectively. The specificity of the LA test is 100% (14).

Latex Agglutination (LA)

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